Mahathi College of Pharmacy is among the leading colleges in Andhra Pradesh for pharmaceutical education. The selection of eligible candidates to join the college is based on various entrance examinations for a fair and impartial selection based on merit. The academic year usually starts between August and September, corresponding to the commencement of the admission cycle in Mahathi College of Pharmacy .

For undergraduate courses, admission into B. Pharma and Pharma. D is held through the Andhra Pradesh Engineering Agriculture and Medical Common Entrance Test (AP EAMCET). The examination for Mahathi College of Pharmacy admission of postgraduates to the M. Pharma course is done through the Post Graduate Engineering Common Entrance Test (AP PGECET). Candidates desiring Mahathi College of Pharmacy admission to the B.