Mar Gregorios College of Arts and Science, Punnapra, is a co-educational college. Mar Gregorios College of Arts and Science admission has also set up an organised process for the selection of students so that only the most deserving ones can take the courses within the institution. The Mar Gregorios College of Arts and Science admission process generally begins a few months before the start of each academic year.

Eligibility criteria for Mar Gregorios College of Arts and Science admission vary with the course opted. In general, for undergraduate courses, students must have passed 10+2 from a recognised board. For postgraduate courses at Mar Gregorios College of Arts and Science, Punnapra , a relevant bachelor's degree is required. Different programmes may have specific subject requirements and minimum percentage criteria.