MES College of Nursing is the first and the only institution in Kerala for women's nursing. It is affiliated to Kerala University of Health Sciences, Thrissur, and is recognised by the Indian Nursing Council (INC) with a rich choice of nursing education programmes to meet the continually changing health needs.

MES College of Nursing admission involves a highly competitive admission process through which it chooses the most meritorious of applicants for the various nursing programmes it offers. This college has a merit-based admission system for students defined and strictly regulated by the Indian Nursing Council, Kerala Nurses and Midwife Council, and Kerala University of Health Sciences.