The diocese of the college is affiliated with the University of Manarcadu in Kottayam, Kerala, thus making St. Mary's College Kottayam an unaffiliated college. It also offers several undergraduate and postgraduate courses in varied disciplines. The processes of St Mary's College admission are designed to be inclusive and merit-based so that only the most qualified candidates are admitted into any given programme.

St Mary's College admission process will usually start after announcing the results of higher secondary with due transparency. St. Mary's College Application Process Follow the guidelines outlined for the application process to St. Mary's College, Kottayam : Admission notices are released by the college on its official website and through local newspapers.